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germline noun[ C ] biology specialized(alsogerm line, germ-line)uk /ˈdʒɜːm.laɪn/ us /ˈdʒɝːm.laɪn/ a series of germ cells(= sperm or egg cells) that develop from earlier cells, containing genetic material that can be passed on, or the genetic material itself: There will be people who want to be the first to successfully modify a human germline. These breast cancer susceptibility genes are commonly mutated in the germline of 5-10% of all breast cancer cases. germline cellMeiosis begins with the germ line cells, which are diploid. germline mutationThe disease is associated with germ-line mutations. When this technology is applied to "germ cells" – the sperm and eggs – or embryos, it changes the germline. It is unknown which stages of embryo development are susceptible to BVDV infection and whether transmission through the female germline is possible. Germ lines can deteriorate and cause extinction of lineages. Germ-line editing could be used to shape the health of tomorrow's kids. SMART Vocabulary: related words and phrases Cells actin anaphase anti-platelet assort axoplasm histography homologous chromosomes infiltration intercellular intermitotic nerve fibre neurofibril neurofibrillary neuroglia neuroglial tetrad thrombocyte thymocyte turgor unciliated
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