| 词汇 | modafinil |
| 语种 | 英语、汉语、英汉翻译、汉英翻译 |
| 释义 | BETA Examples of modafinilmodafinil isn’t in the Cambridge Dictionary yet. You can help! The research described was a proof-of-concept study to examine the cognitive effects of a single dose of modafinil in schizophrenia. In contrast to these other uncontrolled reports, our trial did not reveal a greater impact on negative symptoms for modafinil. Encouragingly, several larger studies examining the effects of modafinil in schizophrenia are also underway. Dopaminergic-adrenergic interactions in the wake promoting mechanism of modafinil. Central alpha 1-adrenergic stimulation in relation to the behaviour stimulating effect of modafinil; studies with experimental animals. No significant worsening of psychopathology was observed and modafinil was well-tolerated. The results of this study demonstrate that, in high-functioning patients with schizophrenia, modafinil is associated with a specific pattern of cognitive enhancement. It is too early to anticipate how modafinil might be incorporated into treatment frameworks. First, modafinil may simply not be effective for negative symptoms in schizophrenia. The precise mode of action of modafinil remains unknown. Among other sleep disorders, four patients noticed difficulties in falling asleep in each group, and one patient had excessive daytime sleepiness in the modafinil group. Cognitive enhancing effects of modafinil in healthy volunteers. The role of wakefulness stimulating agents such as modafinil in this, the hypoactive subtype of delirium, remains to be assessed. This suggests that even at lower doses, modafinil was not superior to placebo in this study. The patients were treated with either modafinil or placebo for 8 weeks. However, modafinil treatment was associated with a greater rate and degree of global improvement at study endpoint compared with placebo. Identifying a subgroup of patients with sleepiness or sleep disorders might help to identify the patients that could be improved by modafinil. Further work is needed to determine the full extent of the effects of modafinil in these patients and the best approach for establishing treatment algorithms. More rigorously designed trials suggest that the clinical effects of modafinil in major depression are limited. |
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