amputate
His doctors told him he faces amputation if he overstresses the leg right now.
She suffered a double fracture and avoided amputation only because of speedy medical attention.
Diabetes can lead to blindness, nerve damage, and leg amputation.
He underwent an amputation of his left hand and forearm after a workplace accident.

SMART Vocabulary: related words and phrases

Medical treatment: surgery
ablate
ablation
adenoidectomy
adrenalectomy
allograft
anaesthesia
anaesthesiology
blood transfusion
endonasal
enterostomy
enucleate
enucleated
enucleation
general anaesthetic
pump something out
reduction mammaplasty
regraft
reimplant
reimplantation
suture

You can also find related words, phrases, and synonyms in the topics:

Cutting off and disconnecting