| 词汇 | disulfide |
| 语种 | 英语、汉语、英汉翻译、汉英翻译 |
| 释义 | BETA Examples of disulfidedisulfide isn’t in the Cambridge Dictionary yet. You can help! The disulfide crosslinking experiment does not prove that the crystal structure of the hammerhead ribozyme is the catalytically active structure. The reduction of a disulfide is a two-electron process while ferredoxin is a one-electron carrier. Overcoming residual frustration in domain-swapping: the roles of disulfide bonds in dimerization and aggregation. Both ribozymes were active within a factor of two of wild-type activity when the disulfide bond was reduced. Assembly of functional rhodopsin requires a disulfide bond between cysteine residues 110 and 187. The disulfide bond that is normally formed by cysteine residues at positions 126 and 203 is indicated by a dashed line. Upon reduction of the disulfide by thioredoxin, the insertion is destabilized, as seen in the spinach structure, and the strands are released. There is a stretch of 11 residues separating the two cysteines involved in the disulfide. In this step, one electron from the ferredoxin and one electron from the iron-sulfur cluster are used to cleave the disulfide bridge. The structure of the enzyme was recently determined and provides the framework for this reduction revealing close contacts between the iron-sulfur center and the disulfide. This is an indication that the endopeptidase has peptide chains connected by disulfide bridges. These disulfide bridges are primary contributors to the 3-dimensional structure of the protein, as there is limited secondary structure. However, as they note, no such cysteine-sulfide disulfide has been observed previously. In each of the extensions is one regulatory disulfide bridge present. An intact interchain disulfide bond is required for the neurotoxicity of tetanus toxin. |
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