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acromegaly noun[ U ] medical specializeduk /ˌæk.rəˈmeɡ.əl.i/ us /ˌæk.rəˈmeɡ.əl.i/ a disease in which the bones of the head, hands, and feet grow larger than normal, caused by the pituitary gland producing too much growth hormone : In acromegaly, the pituitary gland releases large amounts of growth hormone, leading to abnormal growth of the skeleton. These tumours make growth hormone, which can cause acromegaly or gigantism when too much is made. Acromegaly is nearly always caused by a pituitary adenoma. Patients with untreated or persistent acromegaly tend to have premature cardiovascular disease. All patients had typical clinical features of the acromegaly syndrome. SMART Vocabulary: related words and phrases Problems with bones, joints & teeth achondroplasia ankylosed ankylosis anti-plaque anti-rachitic caries carpal tunnel syndrome Ehlers-Danlos syndrome fissure gap-toothed gouty growing pains herniated disc kyphosis tartar tennis elbow TMD TMJ trigger finger water on the knee |