estranged
Over time, estrangements have a serious emotional impact.
They reunited after a two-year estrangement.
Reaching a trade agreement is a tough prospect in light of the two nations' long-standing estrangement.
Many people feel a sense of estrangement from both main political parties.
SMART Vocabulary: related words and phrases Anxiety and worry - general words
agita
agitation
angst
anti-stress
apprehension
break out in a cold sweat
heebie-jeebies
jitters
nerve
nervousness
oppression
overwork
panic attack
strain
tension
tizzy
to someone's consternation
trepidation
uneasiness
willie
You can also find related words, phrases, and synonyms in the topics:
Not being friendly
Isolating and separating